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MUST READ: 5 Signs Your Abdominal Pain is Cause for Concern

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If you’re human and breathing, chances are you get a stomachache now and then. With so many culprits that can cause discomfort – from stress to indigestion to appendicitis – it can be confusing to tell whether your upset tummy is cause for concern. While it never hurts to call a doctor if you’re concerned, there are a few instances when you undoubtedly should.

There’s blood

If you’ve noticed blood in your urine or stool, your abdominal pain is likely caused by something more serious than your ill-advised lunch. Blood in the urine is a symptom of kidney stones, according to eMedicineHealth, and blood in the stool (which is usually dark and tarry rather than bright red) can indicate a number of serious infections and conditions.

It’s localized

If you can pinpoint exactly where the pain is located in your abdomen, it might be time to call the doctor. According to FamilyDoctor.org, pain in the upper middle or upper right sections of the abdomen can be caused by gallstones or a gallbladder infection. Pain near the groin could indicate kidney stones or a bladder infection, and pain in the lower right side of the abdomen may be a sign of ulcerative colitis, Crohn’s disease or other inflammatory diseases.

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